DYSREGULATED PROINFLAMMATORY AND FIBROGENIC PHENOTYPE OF FIBROBLASTS IN CYSTIC FIBROSIS.




Gene Expression Profiling in Postmortem Rett Syndrome Brain: Differential Gene Expression and Patient Classification

The identification of mutations in the transcriptional repressor methyl-CpG-binding protein 2 (MECP2) gene in Rett Syndrome (RTT) suggests that an inappropriate release of transcriptional silencing may give rise to RTT neuropathology.Despite this progress, the molecular basis of RTT neuropathogenesis remains unclear.Using multiple cDNA microarray t

read more

Investigation of the growth patterns of non-functioning pituitary macroadenomas using volumetric assessments on serial MRI investigations

Background: Benign non-functioning pituitary macroadenomas (NFMA) read more often cause mass effect on the optic chiasm necessitating transsphenoidal surgery to prevent blindness.However, surgery is complicated and there is a high tumour recurrence rate.Currently, very little is known about the natural (and residual post-surgical) growth patterns o

read more